Synthesis of Carboxylic Acids - Chemgapedia.
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Synthesis of Carboxylic Acids. There are many possible synthetic pathways that yield carboxylic acids. Some of these are further discussed below. Alcohols and aldehydes may be oxidized into carboxylic acids. Alkenes may be converted into carboxylic acid through oxidative cleavage of the double bond with neutral or acid permanganate, for instance. However, the alkene must contain at least one.Instead, the synthesis of carboxylic acid anhydrides may, for instance, be achieved by treating carboxylate anions with acyl chlorides. Fig.4 Synthesis of heptanoic acid anhydride. Much like in the Fischer esterification, the mechanism of this reaction is an addition-elimination mechanism in which the chloride anion is the leaving group. In the initial reaction step, the carboxylate anion's.
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